Which statement describes calcification or acquired aortic stenosis?

Which statement describes calcification or acquired aortic stenosis?

• A. Calcification or acquired
• B. Infectious
• C. Degenerative
• D. Acute inflammatory

Answer: (A)

Acquired aortic stenosis most often results from calcific degeneration of the aortic valve leaflets. Calcium deposits gradually build up on the cusps, causing stiffness and narrowing of the valve opening, which is the hallmark of the stenosis observed in adults. This mechanism is acquired and degenerative in nature, unlike infectious processes that produce vegetations or inflammatory causes like rheumatic disease that lead to leaflet fusion rather than isolated calcification. So describing the lesion as calcification or an acquired (degenerative) calcific process best fits the typical pathophysiology.

Acquired aortic stenosis most often results from calcific degeneration of the aortic valve leaflets. Calcium deposits gradually build up on the cusps, causing stiffness and narrowing of the valve opening, which is the hallmark of the stenosis observed in adults. This mechanism is acquired and degenerative in nature, unlike infectious processes that produce vegetations or inflammatory causes like rheumatic disease that lead to leaflet fusion rather than isolated calcification. So describing the lesion as calcification or an acquired (degenerative) calcific process best fits the typical pathophysiology.